Chronic myeloid leukemia is one of the onco-hematologic diseases in which the identification of Tools disease markers and therapeutic advances have been particularly impactful.Despite this, significant gaps remain in our understanding of disease pathogenesis, progression, mechanisms of immune escape, and resistance to standard therapies.Recently, a
Empirically-derived dimensions of childhood adversity and cumulative risk: associations with measures of depression, anxiety, and psychosis-spectrum psychopathology
Background: Investigating different approaches to operationalizing childhood adversity and how they relate to transdiagnostic psychopathology is relevant to advance research on mechanistic processes and to inform intervention efforts.To our knowledge, previous studies have not used questionnaire and interview measures of childhood adversity to exam
CLIMADA v1.4.1: towards a globally consistent adaptation options appraisal tool
Climate change is a fact; therefore, adaptation to a changing environment is a necessity.Adaptation is ultimately local, yet similar challenges pose themselves to decision-makers all across the globe and on all levels.The Economics of Climate Adaptation (ECA) methodology has established an economic framework to fully integrate risk and reward persp
Seasonal differences in jump performance in the Svalbard rock ptarmigan (Lagopus muta hyperborea)
Fat storage is essential to the survival of many bird species, providing energy reserves, but can have an effect on locomotor performance with an Accent Table (Set of 3) associated potential increase in predation risk.In particular, the ability to initiate flight through jumping is critical to predator avoidance and may be influenced by changes in
Notions regarding the design of suction systems for industrial ventilation
Air flow in ducts is one of the basic processes of ventilation and air conditioning.Knowledge of this phenomenon and the laws according to it is indispensable for drawing up the sizing calculations of the duct networks, for determining the energy needed to move the air as well as for determining the aerodynamic parameters related to the ventilation